Promotion of film coating technology to improve the quality of Chinese patent medicine tablet - coating technology, thin film coating technology and p
Summary : This comprehensive introduction to film coating technology in China Chinese patent medicine Preparation of industrial tablet production application status, as vigorously promote the advanced technology to improve the quality of proprietary Chinese medicines, tablets, a reference to enhance production levels.
Keywords : Film coating powder, Chinese patent medicine tablets, operating techniques. Film coating technology, which refers to a variety of chemical stability of the strong inertia of the physical properties of polymers and molecular differences in arrangement and structural characteristics, through a scientific formula, in the mild processing conditions, do not change its chemical properties, activation of a specific group of such polymers, activated surface activity, alter the molecular arrangement of a single material to form a mixture of new film, that film coating powder. In the film coating powder with a solvent (usually water or different concentrations of alcohol) to form a mixture of dispersed by the spray film coating, the object form of plastic film several microns thick layer of coating material on the processing, with good protective effect, this process is what we call thin-film coating technology. Since the 90s of last century, film coated tablet technology for proprietary Chinese medicine production, greatly enhanced the level of our proprietary formulation of industrial production and quality of Chinese patent medicine tablets.
Compared with traditional proprietary sugar-coated tablet, film coated tablets of proprietary Chinese medicines are 8 major advantages:
First, the tablets of good quality and high grade of products, greatly enhance the technology content of our proprietary industry;
Second, smaller tablet weight increase and improve the efficacy of proprietary Chinese medicines, tablets; Third, coating speed, short production cycle, low energy consumption, high efficiency; Fourth, the coating process is simple, labor-intensive small and easy promotion applications; Fifth, tablet moisture effective, convenient warehousing management and transport; Sixth, sugar-free, expanded populations of proprietary Chinese medicines and medication tablets the market; Seventh, film coated tablets stability and good high inner quality; Eighth, coating technology can be standardized or NC, for the requirements of the development of modern industrial production or management.
Technical advantages over proprietary thin film coating, are produced Operate Are widely recognized and the consumer market, sales increased rapidly. Film coated tablets proprietary production technology in China has been very mature, with the popularization and application of a variety of conditions, not too long period of time, a great tendency to completely replace proprietary sugar coated! However, the introduction of film coating technology short time in China, manufacturers in the proprietary Chinese medicines, there are still many errors, producers lack the understanding of the technology. Here, we can discuss with each other to share, to raise awareness, to promote proprietary tablet film coating technology forward.
First, the production costs of film coating technology 20 century and the early 50s, the first time for Medicine Preparation of industrial production of Western film coated tablets in the United States was born, after over half a century of development, the technology of industrial production in the world, the field of pharmaceutical preparations have been widely used. Compared with Western films, application of proprietary tablet film coating technology are very different, the introduction of relatively late our time. Official film coating technology applied to the production of our proprietary tablet, it is only in the late 90s of last century, a short time. Proprietary thin film coating technology to promote the use of industrial production the initial stage of preparation as coating of powder or powder required to produce a variety of film coating and coating raw materials Machinery and equipment , Must be imported from abroad, expensive, film coating technology and high production costs, high prices of proprietary thin film coated tablets, which hindered the process of popularization and application of this technology. In recent years, the materials required for thin film coating technology is basically the localized, low cost, sugar-coated tablet has been gradually approaching the cost of production of traditional Chinese patent medicines, the production technology is very mature and promote the use of entering the golden age.
From the current overall situation, thin film coating technology in the production cost of proprietary Chinese medicines in tablet, powder coating, if only just from the price of raw materials or related terms, and still has some sugar-coated tablet gap. Of the overall technology to examine the entire process of film coating technology for the production costs of proprietary Chinese medicine tablet has basically similar, or even with the sugar coated flat, and there is still room for a larger decline in production costs. Proprietary thin film coating technology coupled with economic and social benefits in itself, is far more than sugar coated. This is also in recent years, film coated tablet technology for proprietary Chinese Industrial Production by the rapid development of proprietary Chinese medicines film coated tablets substantial increase in sales of the main market, timely introduction of film coating technology to the advanced technology for the production, which should be attached great importance to manufacturers.
Second, the film coating is a complete set of integrated technologies Different production technologies and sugar coated tablets, film coated tablets proprietary production process is a complete integrated technology, all aspects are indispensable. Such as thin film coating technology on the proprietary chip core hardness, surface finish, optional accessories, technical operation, and so on and sugar coated production techniques vary widely. If you borrowed a sugar-coated tablet production methods or technology, proprietary thin film coating applied to films, often not achieve the desired effect, or even into a different medium Drugs Species, due to the die surface properties are different and can not use the same coating of powder or coating method. Many pharmaceutical manufacturers introduce film coating technology to produce proprietary coated films, the results unsatisfactory, achieving its purpose, the crux of the due to this.
Following the traditional methods of production accessories or proprietary chip core processing for the production of thin film coated tablets, often fail to meet requirements appear tablet disintegration time, hardness of tablet cores poor, rough and a series of one-sided issue resulting in proprietary Chinese medicines of poor quality film coated tablets. To solve these problems, the most effective way is to start from the new selection of accessories, to adjust the feed formula, production technology and related operating procedures be amended accordingly and so on. In particular, the choice to use the new accessories is very important in Europe and the United States has developed rapidly, and thus derive a new industry?? (Pharmaceutical) fine accessories. Proprietary formulation of industrial enterprises in the active introduction of film coating technology, it is also should be a higher level or point of view, but also on the level of the enterprise's own production technology to conduct a scientific adjustment and the opportunity to serve two purposes, to enhance the overall management .
Third, rational use of thin film coating powder
Sugar coated production
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